NEW YORK (AP) — Christina Applegate has revealed her doctor says she was misdiagnosed with multiple sclerosis. She shared this Monday on her podcast “MeSsy” with co-host Jamie-Lynn Sigler. Applegate first announced her MS diagnosis in 2021. She still experiences symptoms like needing a wheelchair despite the misdiagnosis. She says the news is confusing, especially since she and Sigler have become advocates for MS awareness. Applegate feels she has let people down. Applegate has been open about her health struggles in her memoir.
Christina Applegate Misdiagnosed With MS
October 20, 2026 1:25 pm