DUBAI, United Arab Emirates (AP) — Israel has attacked Iran’s capital in strikes that targeted the country’s nuclear program and raised the potential for an all-out war between the two bitter Middle East adversaries. It appeared to be the most significant attack Iran has faced since its 1980s war with Iraq. Multiple sites around the country were hit, including Iran’s main nuclear enrichment facility, where black smoke could be seen rising into the air. The leader of Iran’s paramilitary Revolutionary Guard, Gen. Hossein Salami and chief of staff of Iranian armed forces, Gen. Mohammad Bagheri, were also confirmed dead, representing a significant blow to Tehran’s governing theocracy and an immediate escalation of its long-simmering conflict with Israel.